Flucloxacilline

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01C - Beta-Lactam Antibacterials, Penicillins -> J01CF - Beta-Lactamase Resistant Penicillins -> J01CF05 - Flucloxacillin
Administration category: Free Medicine group: antibacterial Brand name: Floxapen

Safety margins

≥ 18 years
WeightROADosage
ROA:
po
Dosage:
min. 500mg 3 dd
ROA:
iv
Dosage:
min. 500mg 3 dd to max. 2000mg 6 dd
Comments:

Bij obesitas bovengrens van dosering aanhouden, zie https://amsterdamumc.adult.swabid.nl/node/497959

Kidney function

≥ 18 years
ROAGFRDosageIntervalComments
ROA: iv
GFR:
<10
Dosage:
bij behandeling van endocarditis max. 6 g per 24 uur als continue infusie, bij overige indicaties 1 g elke 8-12 uur
Renal elimination: 55%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: Intraveneuze infusie: endocarditis: max 6 g per 24 uur als continue infusie. Overige indicaties: 1 g elke 8-12 uur.

Hemo dialysis: Intraveneuze infusie: endocarditis: max 6 g per 24 uur als continue infusie. Overige indicaties: 1 g elke 8-12 uur.

CAV / VVHD: Intraveneuze infusie: endocarditis: max 6 g per 24 uur als continue infusie. Overige indicaties: 1 g elke 8-12 uur.

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-500182.1
Updated: 03/23/2021 - 14:55
Status: Published

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