Amfotericine B

J - Antiinfectives For Systemic Use -> J02 - Antimycotics For Systemic Use -> J02A - Antimycotics For Systemic Use -> J02AA - Antibiotics -> J02AA01 - Amphotericin B
Administration category: Free Medicine group: antifungal Brand name: Fungizone

Safety margins

≥ 18 years
WeightROADosage
ROA:
iv
Dosage:
min. 0.5mg/kg 1 dd to max. 1.5mg/kg 1 dd
Comments:

Bij obesitas doseren op werkelijk lichaamsgewicht, zie https://amsterdamumc.adult.swabid.nl/node/497959

Kidney function

Renal elimination: 5%
Dosage: independent on kidney function

Interactions

Interaction with (ATC): Expected effect:
Interaction with (ATC):
L04AD01 - Ciclosporin
Expected effect:
verhoogde kans op nefrotoxiciteit
Interaction with (ATC):
C01AA05 - Digoxin
Expected effect:
verhoogde kans op toxiciteit (door kalium depletie)
Interaction with (ATC):
J02AX01 - Flucytosine
Expected effect:
synergisme van werking en toxiciteit

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-500148.1
Updated: 03/16/2021 - 11:51
Status: Published

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