Histoplasmose gedissemineerd
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: amfotericine B liposomaal (Ambisome) iv 3mg/kg 1dd |
Remarks:
Indien CNS betrokkenheid dosering ophogen naar 5mg/kg 1dd. |
|
Priority: 2nd choice |
Medication: itraconazol po loading dose 800mg, 200mg 2dd |
Sources
-
Pubmed.gov publication # 17806045
IDSA treatment guidelines: Clin Infect Dis 45;807,2007
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
Menu position
Metadata
Swab vid: G-461677.3
Updated: 06/18/2020 - 12:08
Status: Published
General comments
Bij goede respons na 2 weken overgaan op itraconazol po 200mg 2 dd, itraconazol spiegels bepalen (apotheek).
Totale duur van de behandeling 1 jaar mits CD4 langer dan 6 maanden > 150 zijn.
In alle andere gevallen doorgaan met secundaire profylaxe: itraconazol 200mg 1 dd.